Find a Location

Find a Location

  Use My Current Location

    Potential Side Effects

    It is important to HerKare that you understand the risks and benefits associated with Hormone Replacement Therapy (HRT) before beginning or continuing treatment. HRT is not a new area of medicine; however, the treatment modalities employed by HerKare may involve innovative therapies. The hormones prescribed as part of treatment may include Estrogen, Progesterone, and Testosterone, as well as other treatments for thyroid function and Vitamins D and B12, where indicated. Testosterone therapy is a treatment that may be used to raise a woman’s sexual interest, muscle mass, or physical function.

    Testosterone therapy is sometimes used for women who are on estrogen therapy, have had their ovaries removed, or suffer from an adrenal system problem or hypopituitarism. It is associated with the relief of symptoms of menopause (hot flashes, vaginal dryness, incontinence and urinary urgency), and may enhance mental clarity and focus.

    In some instances, testosterone therapy has been shown to increase bone density, decrease body fat and cellulite, and increase lean muscle mass.

    Some studies associate testosterone therapy with reduced cardiac risk, and breast-protection, particularly for patients on estrogen therapy.

    When the Food and Drug Administration (FDA) approves a drug for medical use, the manufacturer produces a “label” to explain its use. Once the FDA approves a medication, physicians may use it “off-label” for other purposes if they are well informed about the product, base its use on firm scientific principles and sound medical evidence, and maintain records of its use and effects. Testosterone is approved by the FDA only for use in men. This means that physician-directed low-dose testosterone therapy in women is “off-label.” Because testosterone therapy is “off-label,” your health insurance may not provide coverage for testosterone therapy. This means that you will be required to pay for these services when they are rendered.

    You can learn more about side effects and contraindications for these drugs by contacting your Provider or the FDA at 1-800-FDA-1088 or visit FDA – Safety & Adverse Event Reporting Program. HRT is not for women who are thinking about or could become pregnant. There are a number of potential side effects related to HRT. Generally, these side effects could include bloating, breakthrough bleeding, breast swelling and tenderness, clitoral enlargement, fluid retention, weight gain, liver cysts, mood swings, increased red blood cells, acne, hair growth, vocal changes, or heightened cholesterol levels. In some patients there could be increased risks of endometrial, uterine, or breast cancer, blood clots, stroke, gallbladder disease, or high blood pressure. Certain types of HRT have a higher risk, and each woman’s own risks can vary depending upon her health history and lifestyle, so it is important to talk to your Provider before commencing therapy.


    It is with heavy hearts that we announce that Dr. Sridevi Panchamukhi will be discontinuing her affiliation with HerKare. Dr. Panchamoukhi’s last day with HerKare was Monday, March 27, 2023. As a patient you may obtain copies of your medical records or arrange transfer of your medical records to another physician. HerKare Physician Group, PLLC will continue to maintain your medical records. You may reach out to to obtain copies of your records. We wish Dr. Panchamoukhi the very best.